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Aspirin is the genericized trademark for acetylsalicylic acid (ASA), a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and inflammation, and as an antithrombotic. [10] Specific inflammatory conditions that aspirin is used to treat include Kawasaki disease , pericarditis , and rheumatic fever .
Aspirin-modified COX-2 produces 15-epi-lipoxins, which act to resolve inflammatory responses similar to other lipoxins. [7] Newer NSAID drugs called COX-2 selective inhibitors have been developed that inhibit only COX-2, with the hope for reduction of gastrointestinal side-effects. [8]
Non-steroidal anti-inflammatory drugs [1] [3] (NSAID) [1] are members of a therapeutic drug class which reduces pain, [4] decreases inflammation, decreases fever, [1] and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of gastrointestinal ulcers and bleeds ...
Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs , also called anti-inflammatories , make up about half of analgesics .
The mechanism of aspirin's analgesic, anti-inflammatory and antipyretic properties was unknown through the drug's heyday in the early- to mid-twentieth century; Heinrich Dreser's explanation, widely accepted since the drug was first brought to market, was that aspirin relieved pain by acting on the central nervous system.
The active ingredient, diclofenac sodium, is a nonsteroidal anti-inflammatory drug (NSAID) that temporarily blocks the production of pain-signaling chemicals called prostaglandins, treating pain ...
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