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Bioglass 45S5 or calcium sodium phosphosilicate, is a bioactive glass specifically composed of 45 wt% SiO 2, 24.5 wt% CaO, 24.5 wt% Na 2 O, and 6.0 wt% P 2 O 5. [1] Typical applications of Bioglass 45S5 include: bone grafting biomaterials , repair of periodontal defects, cranial and maxillofacial repair, wound care, blood loss control ...
Some Sensodyne products contain calcium sodium phosphosilicate CSPS (Novamin), which appears to help with tooth sensitivity. [5] [6] A randomized clinical trial published in 2015 demonstrated that dentifrices containing 5% CSPS may have the potential to mineralize and occlude the dentine in the oral environment.
Betaxolol effectively prevents the increase of intracellular calcium, which leads to increased production of the aqueous humor. In the context of open angle glaucoma, increased aqueous humor produced by ciliary bodies increases intraocular pressure, causing degeneration of retinal ganglion cells and the optic nerve.
Eye drops or eyedrops are liquid drops applied directly to the surface of the eye usually in small amounts such as a single drop or a few drops. Eye drops usually contain saline to match the salinity of the eye. Drops containing only saline and sometimes a lubricant are often used as artificial tears to treat dry eyes or simple eye irritation ...
One suspected pharmacodynamic mechanism is the blocking of IgE-regulated calcium channels. Without intracellular calcium, the histamine vesicles cannot fuse to the cell membrane and degranulate. [1] As inhalers they are used to treat asthma, as nasal sprays to treat hay fever (allergic rhinitis) and as eye drops for allergic conjunctivitis. [2]
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The sodium-calcium exchanger (often denoted Na + /Ca 2+ exchanger, exchange protein, or NCX) is an antiporter membrane protein that removes calcium from cells. It uses the energy that is stored in the electrochemical gradient of sodium (Na +) by allowing Na + to flow down its gradient across the plasma membrane in exchange for the countertransport of calcium ions (Ca 2+).
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