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Qualitative urine pregnancy tests vary in sensitivity. High-sensitivity tests are more common and typically detect hCG levels between 20 and 50 milli-international units/mL (mIU/mL). Low-sensitivity tests detect hCG levels between 1500 and 2000 mIU/mL and have unique clinical applications, including confirmation of medication abortion success. [12]
The term "multiple-marker screening test" is sometimes used instead. [1] [2] This term can encompass the "double test" and "quadruple test" (described below). The Triple screen measures serum levels of AFP, estriol, and beta-hCG, with a 70% sensitivity and 5% false-positive rate.
The triple test measures serum levels of AFP, estriol, and beta-hCG, with a 70% sensitivity and 5% false-positive rate. It is complemented in some regions of the United States, as the Quad test (adding inhibin A to the panel, resulting in an 81% sensitivity and 5% false-positive rate for detecting Down syndrome when taken at 15–18 weeks of ...
Pregnancy tests fall into two categories: at-home urine tests and the in-office blood test. At-home urine tests have different thresholds for the level of hCG they’re looking for, Dr. Ahmad says.
As pregnancy tests, quantitative blood tests and the most sensitive urine tests usually detect hCG between 6 and 12 days after ovulation. [25] It must be taken into account, however, that total hCG levels may vary in a very wide range within the first 4 weeks of gestation, leading to false results during this period. [26]
While the specificity and positive predictive value are poor, fetal fibronectin testing has excellent sensitivity (100%) and negative predictive value (100%). Therefore, a negative fFN test is a very strong indicator that preterm birth is not likely to occur within the next 7 days. [ 5 ]
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