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As globus sensation is a symptom, a diagnosis of globus pharyngis is typically a diagnosis of exclusion. If globus sensation is presenting with other symptoms such as pain, swallowing disorders such as aspiration or regurgitation (dysphagia), weight loss, or voice change, [ 10 ] an organic cause needs to be investigated, typically with endoscopy .
Laryngopharyngeal reflux (LPR) or laryngopharyngeal reflux disease (LPRD) is the retrograde flow of gastric contents into the larynx, oropharynx and/or the nasopharynx. [4] [5] LPR causes respiratory symptoms such as cough and wheezing [6] and is often associated with head and neck complaints such as dysphonia, globus pharyngis, and dysphagia. [7]
Globus pharyngeus (feeling like there is a lump in the throat) Cold or flu-like symptoms (which, like a cough, may also be a causal factor for laryngitis) Swollen lymph nodes in the throat, chest, or face; Fever; General muscle pain ; Shortness of breath, predominantly in children
Treatment strategies will differ on a patient to patient basis and should be structured to meet the specific needs of each individual patient. Treatment strategies are chosen based on a number of different factors including diagnosis, prognosis, reaction to compensatory strategies, severity of dysphagia, cognitive status, respiratory function ...
It lies inferior to the epiglottis and extends to the location where this common pathway diverges into the respiratory and digestive pathways. At that point, the laryngopharynx is continuous with the esophagus posteriorly. The esophagus conducts food and fluids to the stomach; air enters the larynx anteriorly.
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Furthermore, Omophydroid Muscle Syndrome - a rare muscle condition which causes chronic soreness and pain swallowing, may be the cause of falsely diagnosed pseudodysphagia. It is also not uncommon for pseudodysphagia to be misdiagnosed with conversion disorder (Globus Pharyngeus) and eating disorders.
Abnormalities can cause constrictions within the esophagus. Globus pharyngis – commonly referred to as lumps in ones throat [5] Myasthenia gravis – the thymus gland is thought to be necessary for the deletion of auto-reactive T cells, and seems to have an important role in the pathogenesis of myasthenia gravis.