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Graphic depicting the human skin microbiota, with relative prevalences of various classes of bacteria. The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [1] [2] including the gastrointestinal tract, skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung ...
The Human Microbiome Project (HMP) was a United States National Institutes of Health (NIH) research initiative to improve understanding of the microbiota involved in human health and disease. Launched in 2007, [ 1 ] the first phase (HMP1) focused on identifying and characterizing human microbiota.
The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [117] including the skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung, saliva, oral mucosa, conjunctiva, biliary tract, and gastrointestinal tract.
The five-year project, best characterized as a feasibility study with a budget of $115 million, tested how changes in the human microbiome are associated with human health or disease. [85] The Earth Microbiome Project (EMP) is an initiative to collect natural samples and analyze the microbial community around the globe.
The oral microbiota consists of all the microorganisms that exist in the mouth. It is the second largest of the human body and made of various bacteria, viruses, fungi and protozoa. [ 14 ] These organisms play an important role in oral and overall health.
In humans, gut microecology is the study of the microbial ecology of the human gut which includes gut microbiota composition, its metabolic activity, and the interactions between the microbiota, the host, and the environment. [3] Research in human gut microecology is important because the microbiome can have profound effects on human health.
This is part of the Human Microbiome initiative with primary goals to determine if there is a core human microbiome, to understand the changes in the human microbiome that can be correlated with human health, and to develop new technological and bioinformatics tools to support these goals. [100]
In 2014, the Earth Microbiome project proposed a broad initiative to identify the diversity and importance of the microbiota in different ecosystems across the planet, including free-living microbiota (in water and terrestrial systems) and host associated-microbiota (associated with plants and animals). [7]