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Aspergillosis occurs in humans, birds and other animals. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in people with severely compromised immune systems such as those undergoing bone marrow transplantation. [7]
Chronic pulmonary aspergillosis is a long-term fungal infection caused by members of the genus Aspergillus—most commonly Aspergillus fumigatus. [8] The term describes several disease presentations with considerable overlap, ranging from an aspergilloma [12] —a clump of Aspergillus mold in the lungs—through to a subacute, invasive form known as chronic necrotizing pulmonary aspergillosis ...
Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. [3] The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. [4]
Aspergillus fumigatus is a species of fungus in the genus Aspergillus, and is one of the most common Aspergillus species to cause disease in individuals with an immunodeficiency. Aspergillus fumigatus , a saprotroph widespread in nature, is typically found in soil and decaying organic matter, such as compost heaps, where it plays an essential ...
In addition to organ damage after inhalation of OTA, cases of allergy development have also been found. A disease named allergic bronchopulmonary aspergillosis, has been found to be caused due to the antigenic effects of Aspergillus ochraceus. [32] Aspergillus ochraceus was found to be associated with the development of asthma in children too. [8]
According to the Global Action Fund for Fungal Infections, every year there are over 10 million cases of fungal asthma, around 3 million cases of long-term aspergillosis of lungs, 1 million cases of blindness due to fungal keratitis, more than 200,000 cases of meningitis due to cryptococcus, 700,000 cases of invasive candidiasis, 500,000 cases ...
Caspofungin (INN; [1] [4] brand name Cancidas) is a lipopeptide antifungal drug from Merck & Co., Inc.. [5] It is a member of a class of antifungals termed the echinocandins. [medical citation needed] It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall.
Aspergillus ustus is a microfungus and member of the division Ascomycota. It is commonly found in indoor environments and soil. [ 1 ] Isolated cases of human infection resulting from A. ustus have been described; however the majority of these are nail infections .