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PUMA is involved in p53-dependent and -independent apoptosis induced by a variety of signals, and is regulated by transcription factors, not by post-translational modifications. After activation, PUMA interacts with antiapoptotic Bcl-2 family members, thus freeing Bax and/or Bak which are then able to signal apoptosis to the mitochondria.
The discovery of the Glutamate Receptor Interacting Protein (GRIP-1) came as a result of the observation that Glutamate Receptors, such as the NMDA receptor, cluster at synapses. [2] Shortly after this observation, researchers identified a region on the C-terminal region of NMDA receptors called the tSXV motif that has the ability to bind to ...
Puma is the main producer of enthusiast driving shoes and race suits and entered a partnership with BMW, Ducati and Ferrari to make their respective shoes. [72] In Formula 1, Puma equips the teams of Mercedes AMG Petronas, Scuderia Ferrari, Stake Kick Sauber, and Williams. They also equipped Red Bull Racing until 2022.
RQ-20A Puma Military designation for the Puma All Environment variant. Enhanced Puma Upgrade of the RQ-20A Puma AE with more powerful propulsion system and new batteries that increase endurance by 75 percent to 3.5 hours, auxiliary payload bay to integrate payloads while keeping the video camera, precision navigation system with secondary GPS, and a redesigned durable fuselage with reinforced ...
TikTok creator Joe Smith confirmed that his six-year-old daughter Jules Smith died on Monday, Dec. 9 after she was diagnosed with a fatal brain tumor. In a video captioned "We love you our little ...
December 1, 2024 at 12:03 PM. Police in have revealed tragic new details behind the mysterious death of a 26-year-old Polish newlywed two years after she was found on the streets of Miami.
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