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The upper normal limit of serum prolactin is typically between 15 to 25 ng/mL for both genders. [1] Levels exceeding this range indicate hyperprolactinemia. Prolactin (PRL) is a peptide hormone produced by lactotroph cells in the anterior pituitary gland. [1] It plays a vital role in lactation and breast development. [1]
Prolactin is sometimes classified as a gonadotropin [17] although in humans it has only a weak luteotropic effect while the effect of suppressing classical gonadotropic hormones is more important. [18] Prolactin within the normal reference ranges can act as a weak gonadotropin, but at the same time suppresses gonadotropin-releasing hormone ...
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
The most common complex found in blood consists of prolactin and immunoglobulin G (IgG). [1] While the free prolactin hormone is active, prolactin in the macroprolactin complex does not have any biological activity in the body and is considered benign. [2] However, macroprolactin is detected by all Laboratory tests that measure prolactin in ...
For instance, prolactin and other hormones related to prolactin levels may be associated with anorgasmia. Loss of sensation. Research suggests it’s normal to lose some level of sensitivity with age.
The prevalence of hyperprolactinemia ranges from 0.4% in an unselected normal adult population (10,000 normal Japanese adults working at a single factory) to as high as 9 to 17% in women with reproductive disorders.
Dopamine is the chemical that normally inhibits prolactin secretion, so clinicians may treat prolactinoma with drugs that act like dopamine such as bromocriptine and cabergoline. [12] This type of drug is called a dopamine agonist. [12] These drugs shrink the tumor and return prolactin levels to normal in approximately 80% of patients.
Note: this pathologic range is the one you claim is normal. Prolactin levels < 5 ng / mL constitutes hypoprolactinemia. Here's another paper stating other harmful effects of hypoprolactinemia: Gonzales GF, Velasquez G, Garcia-Hjarles M. Hypoprolactinemia as related to seminal quality and serum testosterone. Arch Androl. 1989;23(3):259-65. PMID ...