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  2. Efanesoctocog alfa - Wikipedia

    en.wikipedia.org/wiki/Efanesoctocog_alfa

    Efanesoctocog alfa is a recombinant DNA-derived, Factor VIII concentrate indicated for use in adults and children with hemophilia A (congenital factor VIII deficiency) for routine prophylaxis to reduce the frequency of bleeding episodes; on-demand treatment & control of bleeding episodes; and perioperative management of bleeding.

  3. Factor VIII (medication) - Wikipedia

    en.wikipedia.org/wiki/Factor_VIII_(medication)

    Factor VIII, an essential blood coagulation protein, [12] is used as a medication to treat and prevent bleeding in people with hemophilia A and other causes of low factor VIII. [13] [14] Certain preparations may also be used in those with von Willebrand's disease. [14] It is given by slow injection into a vein. [13]

  4. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    hemophilia: Lorlatinib [1] Pfizer: ALK-positive, metastatic non-small cell lung cancer: Brentuximab vedotin [1] Seattle Genetics: anaplastic large-cell lymphoma: Eltrombopag [1] Novartis Pharmaceuticals: severe aplastic anemia: Emapalumab [1] Swedish Orphan Biovitrum: hemophagocytic lymphohistiocytosis: Venetoclax [1] AbbVie: acute myeloid ...

  5. FDA Approves Pfizer's Second Hemophilia Drug With Six Months

    www.aol.com/fda-approves-pfizers-second...

    Hemophilia is a family of rare genetic blood diseases caused by a clotting factor deficiency (FVIII in hemophilia A, FIX in hemophilia B), impacting more than 800,000 people globally.

  6. Haemophilia - Wikipedia

    en.wikipedia.org/wiki/Haemophilia

    Haemophilia (British English), or hemophilia (American English) [6] (from Ancient Greek αἷμα (haîma) 'blood' and φιλία (philía) 'love of'), [7] is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding.

  7. Factor VIII - Wikipedia

    en.wikipedia.org/wiki/Factor_VIII

    2157 14069 Ensembl ENSG00000185010 ENSMUSG00000031196 UniProt P00451 Q06194 RefSeq (mRNA) NM_000132 NM_019863 NM_001161373 NM_001161374 NM_007977 RefSeq (protein) NP_000123 NP_063916 NP_001154845 NP_001154846 NP_032003 Location (UCSC) Chr X: 154.84 – 155.03 Mb Chr X: 74.22 – 74.43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Coagulation factor VIII (Factor VIII, FVIII, also ...

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