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  2. Nucleic acid double helix - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_double_helix

    The double-helix model of DNA structure was first published in the journal Nature by James Watson and Francis Crick in 1953, [6] (X,Y,Z coordinates in 1954 [7]) based on the work of Rosalind Franklin and her student Raymond Gosling, who took the crucial X-ray diffraction image of DNA labeled as "Photo 51", [8] [9] and Maurice Wilkins, Alexander Stokes, and Herbert Wilson, [10] and base-pairing ...

  3. Molecular Structure of Nucleic Acids: A Structure for ...

    en.wikipedia.org/wiki/Molecular_Structure_of...

    Other advances in molecular biology stemming from the discovery of the DNA double helix eventually led to ways to sequence genes. James Watson directed the Human Genome Project at the National Institutes of Health. [7] The ability to sequence and manipulate DNA is now central to the biotechnology industry and modern medicine.

  4. Antiparallel (biochemistry) - Wikipedia

    en.wikipedia.org/wiki/Antiparallel_(biochemistry)

    Antiparallel and parallel beta sheet. Many proteins may adopt a beta sheet as part of their secondary structure. In beta sheets, sections of a single polypeptide may run side-by-side and antiparallel to each other, to allow for hydrogen bonding between their backbone chains. Beta sheets can also be either a parallel or anti-parallel secondary ...

  5. Molecular models of DNA - Wikipedia

    en.wikipedia.org/wiki/Molecular_models_of_DNA

    The first reports of a double helix molecular model of B-DNA structure were made by James Watson and Francis Crick in 1953. [ 5 ] [ 6 ] That same year, Maurice F. Wilkins, A. Stokes and H.R. Wilson, reported the first X-ray patterns of in vivo B-DNA in partially oriented salmon sperm heads.

  6. DNA - Wikipedia

    en.wikipedia.org/wiki/DNA

    Each end of the double helix has an exposed 5' phosphate on one strand and an exposed 3′ hydroxyl group (—OH) on the other. DNA is a long polymer made from repeating units called nucleotides . [ 6 ] [ 7 ] The structure of DNA is dynamic along its length, being capable of coiling into tight loops and other shapes. [ 8 ]

  7. Nucleic acid structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure

    B-DNA's favored conformations occur at high water concentrations; the hydration of the minor groove appears to favor B-DNA. B-DNA base pairs are nearly perpendicular to the helix axis. The sugar pucker which determines the shape of the a-helix, whether the helix will exist in the A-form or in the B-form, occurs at the C2'-endo. [13]

  8. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    The structure of the DNA double helix (type B-DNA). The atoms in the structure are color-coded by element and the detailed structures of two base pairs are shown in the bottom right. DNA exists as a double-stranded structure, with both strands coiled together to form the characteristic double helix.

  9. Nucleic acid tertiary structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_tertiary...

    The double helix is the dominant tertiary structure for biological DNA, and is also a possible structure for RNA. Three DNA conformations are believed to be found in nature, A-DNA, B-DNA, and Z-DNA. The "B" form described by James D. Watson and Francis Crick is believed to predominate in cells. [2]

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