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Medications are a common treatment option for people with overactive bladder syndrome. A number of antimuscarinic drugs (e.g., darifenacin, hyoscyamine, oxybutynin, tolterodine, solifenacin, trospium, fesoterodine) are frequently used to treat overactive bladder. [17] Long term use, however, has been linked to dementia.
The front-line treatment for overactive bladder are medications, either daily pills or taken as a preventative before specific occasions Dr. Linehan says. There are two main types: beta agonists ...
Mirabegron is the first clinically available beta-3 agonist with approval for use in adults with overactive bladder. Mirabegron was approved for medical use in the United States and in the European Union in 2012. [8] [9] [3] In 2022, it was the 222nd most commonly prescribed medication in the United States, with more than 1 million prescriptions.
Oxybutynin, sold under the brand name Ditropan among others, is an anticholinergic medication primarily used to treat overactive bladder.It is widely considered a first-line therapy for overactive bladder due to its well-studied side effect profile, broad applicability, and continued efficacy over long periods of time.
Solifenacin, sold as the brand name Vesicare [a] among others, is a medicine used to treat overactive bladder and neurogenic detrusor overactivity (NDO). [1] [2] It may help with incontinence, urinary frequency, and urinary urgency. [3] Benefits appear similar to other medications in the class. [4] It is taken by mouth. [1]
Trospium chloride is a muscarinic antagonist used to treat overactive bladder. [3] It has side effects typical of this class of drugs, namely dry mouth, stomach upset, and constipation; these side effects cause problems with people taking their medicine as directed.
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