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Cannabis use disorder (CUD), also known as cannabis addiction or marijuana addiction, is a psychiatric disorder defined in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders and ICD-10 as the continued use of cannabis despite clinically significant impairment.
Marijuana use is also linked to other substance use disorders including nicotine addiction." [309] It also reported that "These findings are consistent with the idea of marijuana as a "gateway drug". However, the majority of people who use marijuana do not go on to use other, "harder" substances.
The Australian National Household Survey of 2001 [98] found that cannabis is rarely used in Australia without other drugs. 95% of cannabis users also drank alcohol; 26% took amphetamines; 19% took ecstasy and only 2.7% reported not having used any other drug with cannabis. [99]
That same survey found that among underage Americans (12 to 17 years of age), more than 21% had consumed alcohol. ... Marijuana is often pegged as a "classic gateway drug," but one expert said ...
Growing evidence suggests marijuana may be linked to certain heart problems. What's not clear is whether the heart risks are from smoking or if it’s the THC in weed that could be harmful.
For instance, in the 1980s and 1990s, NIMH researchers found that dopamine plays only a marginal role in marijuana's psychoactive effects. [25] Years later, however, NIDA educational materials continued to warn of the danger of dopamine-related marijuana addiction. [26]
Synthetic marijuana compounds began to be manufactured and sold in the early 2000s. [6] From 2008 to 2014, 142 synthetic cannabinoid receptor agonists were reported to the European Monitoring-Center for Drugs and Drug Addiction (EMCDDA). [12]
The 2016 Drug and Alcohol Crash Risk Study found marijuana was the most frequently detected drug other than alcohol; in addition, people using cannabis were more likely to be involved in crashes.