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Metronomic therapy is shown to affect both tumor microenvironment and tumor cells to achieve its therapeutic effects. [1] Metronomic therapy is also cost-effective as a lower dose is used compared to conventional chemotherapy. [2] The use of metronomic therapy has been extensively investigated and can be advantageous in selected group of ...
In elderly patients, it may cause excitement and confusion, while in children, it may result in paradoxical hyperactivity. [37] Phenobarbital is a cytochrome P450 hepatic enzyme inducer. It binds transcription factor receptors that activate cytochrome P450 transcription, thereby increasing its amount and thus its activity. [38]
Nutritional problems are also frequently seen in cancer patients at diagnosis and through chemotherapy treatment. Research suggests that in children and young people undergoing cancer treatment, parenteral nutrition may help with this leading to weight gain and increased calorie and protein intake, when compared to enteral nutrition. [138]
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]
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The refrain of parents is “I love all my children equally.” But not all kids get treated equally. Experts explain the impact of preferential treatment in a family.
In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration. Routes can also be classified based ...
Patients are typically offered testing if they have either a personal or family history of cancer that meets certain criteria, Zakalik adds. Those criteria have broadened over the last few years ...