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The final stage of biofilm formation is known as development, and is the stage in which the biofilm is established and may only change in shape and size. [ citation needed ] The development of a biofilm may allow for an aggregate cell colony (or colonies) to be increasingly tolerant [ 23 ] or resistant to antibiotics .
Quorum sensing (QS) is used by bacteria to form biofilms. Quorum sensing is used by bacteria to form biofilms because the process determines if the minimum number of bacteria necessary for biofilm formation are present. The criteria to form a biofilm is dependent on a certain density of bacteria rather than a certain number of bacteria being ...
The most commonly recognised bacteria that are responsible for initiating the biofilm formation that can eventually lead to caries are streptococcus mutans and lactobacillus. [15] The key factors for virulence include their ability to metabolise glucose and similar sugars, their tolerance for a low pH environment, and their acidogenicity. [ 16 ]
Dental plaque is a biofilm that attaches to tooth surfaces, restorations and prosthetic appliances (including dentures and bridges) if left undisturbed.Understanding the formation, composition and characteristics of plaque helps in its control. [5]
Biofilm formation begins with the initial attachment of microorganisms to a substrate, such as rocks, shells, or sand in the intertidal zone. This process occurs during the reversible attachment phase, in which the microorganisms only lightly adhere to the substrate. [5]
Biofilms are a mixture of microorganisms, layered together and usually adhered to a surface. The advantages of a biofilm include resistance to environmental stresses, antibiotics, and the ability to more easily obtain nutrients. [2] PhoB is used to enhance biofilm formation in environments where Pi is not in sufficient supply.
The formation of biofilms is a complex process and is dependent upon the availability of light as well as the relationships between the microorganisms. Biofilms serve a variety of roles in aquatic, terrestrial, and extreme environments; these roles include functions which are both beneficial and detrimental to the environment.
Biofouling is divided into microfouling—biofilm formation and bacterial adhesion—and macrofouling—attachment of larger organisms. Due to the distinct chemistry and biology that determine what prevents them from settling, organisms are also classified as hard- or soft-fouling types.
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