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In immunology, systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the whole body. [1] It is the body's response to an infectious or noninfectious insult . Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components.
Vitamin D is known as an immune regulator that assists in the adaptive and innate immune response. [86] [87] A deficiency in vitamin D, from hereditary or environmental influence, can lead to a more inefficient and weaker immune response and seen as a contributing factor to the development of autoimmune diseases. [87]
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part. [5] There are at least 80 types of autoimmune diseases. [5] Nearly any body part can be involved. Common symptoms include low-grade fever and feeling tired. [5] Often symptoms come and go. [5]
A cytokine storm may take place, [16] in which the child's innate immune system stages an excessive and uncontrolled inflammatory response. [17] Heart failure is common. [15] Clinical complications can include damage to the heart muscle, respiratory distress, acute kidney injury, and increased blood coagulation. [18]
[6] [131] Identification of the exact nature of the immune process involved in Kawasaki disease could help guide research aimed at improving clinical management. [ 101 ] Inflammation, or vasculitis , of the arteries and veins occurs throughout the body, usually caused by increased production of the cells of the immune system to a pathogen , or ...
Immune reconstitution inflammatory syndrome (IRIS) is a condition seen in some cases of HIV/AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse.
Despite the benefits of treatment, people with autoimmune hepatitis generally have a lower transplant-free survival than the general population. [36] [37] [38] Outcomes with liver transplant are generally favorable with a five-year survival greater than 80 percent. [4] Presentation and response to therapy may differ according to race.