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A microfibril is a very fine fibril, or fiber-like strand, consisting of glycoproteins and cellulose.It is usually, but not always, used as a general term in describing the structure of protein fiber, e.g. hair and sperm tail.
Cellulose microfibrils are made on the surface of cell membranes to reinforce cells walls, which has been researched extensively by plant biochemists and cell biologist because 1) they regulate cellular morphogenesis and 2) they serve alongside many other constituents (i.e. lignin, hemicellulose, pectin) in the cell wall as a strong structural support and cell shape. [15]
The primary cell wall derives its notable tensile strength from cellulose molecules, or long-chains of glucose residues stabilized by hydrogen bonding. [17] Cellulose chains are observed to align in overlapping parallel arrays, with the similar polarity forming a cellulose microfibril.
Microfibrillar-associated protein 2 is a protein that in humans is encoded by the MFAP2 gene. [5] [6]Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases.
“With these older medications, the expectations for patients would be improving their cholesterol, blood glucose numbers or blood pressure,” Moreno told CNN by email this week.
It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs.
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