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Many symptoms are attributed to the development of Hashimoto's thyroiditis. Symptoms can include: fatigue, weight gain, pale or puffy face, feeling cold, joint and muscle pain, constipation, dry and thinning hair, heavy menstrual flow or irregular periods, depression, a slowed heart rate, problems getting pregnant, miscarriages, [19] and ...
neuropsychiatric symptoms (e.g. hallucination, delusion or paranoia) Myoclonus, generalised tonic-clonic or partial seizures; focal-neurological deficits; Elevated titres of thyroid tissue antibodies (TPO-ab or microsomal) Euthyroidism (potentially achieved by treatment with L-T4 or L-T3) or mild hypothyroidism with TSH concentration below 20 mIU/L
Thyroiditis is generally caused by an immune system attack on the thyroid, resulting in inflammation and damage to the thyroid cells. This disease is often considered a malfunction of the immune system and can be associated with IgG4-related systemic disease, in which symptoms of autoimmune pancreatitis, retroperitoneal fibrosis and noninfectious aortitis also occur.
A possible explanation for the mental symptoms of sub-clinical thyroid disease, might be found in the fact that the brain has among the highest expression of THR's [clarification needed], and that neurons are often more sensitive than other tissues to thyroid abnormalities, including sub-clinical hyperthyroidism and thyrotoxicosis.
Thyroid disease is a medical condition that affects the function of the thyroid gland.The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ.
Additionally, patients may present with a variety of symptoms such as palpitations and arrhythmias (notably atrial fibrillation), shortness of breath , loss of libido, nausea, vomiting, and diarrhea. Long term untreated hyperthyroidism can lead to osteoporosis. In the elderly, these classical symptoms may not be present. [citation needed]
There may be symptoms of thyroid overactivity, such as weight loss, a fast or irregular heart rate, tremor, and perspiration; [1] [2] but such symptoms occur in only half of all cases. [5] The most common type of hyperthyroidism, Graves' disease , may additionally cause eye problems ( Graves' ophthalmopathy ) and skin changes of the legs ...
Symptoms may not be typical in the young, old, or pregnant. [2] It usually occurs due to untreated hyperthyroidism and can be provoked by infections. [2] It is a medical emergency and requires hospital care to control the symptoms rapidly. The mortality rate in thyroid storm is 3.6-17%, usually due to multi-organ system failure.
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