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N-Acetylneuraminic acid (Neu5Ac or NANA) is the predominant sialic acid found in human cells, and many mammalian cells. Other forms, such as N-Glycolylneuraminic acid , may also occur in cells. This residue is negatively charged at physiological pH and is found in complex glycans on mucins and glycoproteins found at the cell membrane .
A pyridinecarboxylic acid is any member of a group of organic compounds which are monocarboxylic derivatives of pyridine. Pyridinecarboxylic acid comes in three isomers: Picolinic acid (2-pyridinecarboxylic acid) Nicotinic acid (3-pyridinecarboxylic acid), also known as Niacin; Isonicotinic acid (4-pyridinecarboxylic acid)
Isoxazoles also form the basis for a number of drugs, [9] including the COX-2 inhibitor valdecoxib and a neurotransmitter agonist AMPA. A derivative, furoxan , is a nitric oxide donor. An isoxazolyl group is found in many beta-lactamase-resistant antibiotics , such as cloxacillin , dicloxacillin and flucloxacillin .
Formic acid (HCO 2 H) 3.75 Chloroformic acid (ClCO 2 H) 0.27 [5] Acetic acid (CH 3 CO 2 H) 4.76 Glycine (NH 2 CH 2 CO 2 H) 2.34 Fluoroacetic acid (FCH 2 CO 2 H) 2.586 Difluoroacetic acid (F 2 CHCO 2 H) 1.33 Trifluoroacetic acid (CF 3 CO 2 H) 0.23 Chloroacetic acid (ClCH 2 CO 2 H) 2.86 Dichloroacetic acid (Cl 2 CHCO 2 H) 1.29 Trichloroacetic ...
It is an intermediate product in catabolism of quinaldine in Arthrobacter sp., and is further metabolized to anthranilic acid. [2] [3] N-Acetylanthranilic acid can be synthesized from 2-bromoacetanilide via palladium-catalyzed carbonylation in tri-n-butylamine-water at 110–130 °C, under 3 atm of carbon monoxide. [4]
2-Nitrophenylacetic acid is an organic compound used in organic synthesis that has also been used as an herbicide. It is a derivative of phenylacetic acid , containing a phenyl functional group , a carboxylic acid functional group, and a nitro functional group.
Peramivir (trade name Rapivab) is an antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza.Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells.
Phenylboronic acid or benzeneboronic acid, abbreviated as PhB(OH) 2 where Ph is the phenyl group C 6 H 5 - and B(OH) 2 is a boronic acid containing a phenyl substituent and two hydroxyl groups attached to boron. Phenylboronic acid is a white powder and is commonly used in organic synthesis.