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Niacin may raise heart disease risk, a study finds. Experts share what you need to know about vitamin B3 and its potential to trigger inflammation.
High levels of niacin, an essential B vitamin, may raise the risk of heart disease by triggering inflammation and damaging blood vessels, according to new research.. The report, published Monday ...
N 1-Methyl-4-pyridone-3-carboxamide, also abbreviated as 4PY, is a breakdown product of niacin, [1] that is associated with an increased risk of cardiovascular disease. [2] It has 2 carbonyl groups that are close to each other. [3] [4] [5]
A man with pellagra, which is caused by a chronic lack of vitamin B 3 in the diet. Severe deficiency of niacin in the diet causes the disease pellagra, characterized by diarrhea, sun-sensitive dermatitis involving hyperpigmentation and thickening of the skin (see image), inflammation of the mouth and tongue, delirium, dementia, and if left untreated, death. [7]
Liver disease or kidney disease: Niacin can accumulate in people with liver or kidney problems, potentially worsening their condition. [1] Bleeding disorders: Inositol nicotinate may slow blood clotting, increasing the risk of bleeding for individuals with clotting disorders or those undergoing surgery. [1]
Causes can include: Rheumatic heart disease (a condition that can occur when the bacteria that causes strep throat isn’t treated with antibiotics) Endocarditis (an infection of the inner lining ...
Inflammation of the jejunum or ileum can prevent nutrient absorption, leading to pellagra, and this can in turn be caused by Crohn's disease. [10] Gastroenterostomy can also cause pellagra. [10] Chronic alcoholism can also cause poor absorption, which combined with a diet already low in niacin and tryptophan produces pellagra. [10]
Chest pain can be a sign of heart disease due to high LDL cholesterol or high triglycerides. A gray or white ring around your eyes. High cholesterol levels can cause arcus senilis, which presents ...