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Infectious mononucleosis mainly affects younger adults. [16] When older adults do catch the disease, they less often have characteristic signs and symptoms such as the sore throat and lymphadenopathy. [16] [26] Instead, they may primarily experience prolonged fever, fatigue, malaise and body pains. [16]
Transmission of this virus through the air or blood does not normally occur. The incubation period, or the time from infection to appearance of symptoms, ranges from 2 to 6 weeks with 4 weeks being the most common. Persons with infectious mononucleosis may be able to spread the infection to others for a period of weeks.
Many children who become infected with EBV display no symptoms or the symptoms are indistinguishable from the other mild, brief illnesses of childhood. [21] When infection occurs during adolescence or young adulthood, it causes infectious mononucleosis 35 to 50% of the time. [22] EBV infects B cells of the immune system and epithelial cells.
Symptoms include “sensitivity to light, dizziness, pain behind the eyes, nausea, vomiting, and rash,” the CDC says, while more serious disease includes meningitis, encephalitis, and bleeding.
An online survey conducted by the Cleveland Clinic of 1,174 men 18 years or older, found that 72% of men would rather do household tasks, such as cleaning the bathroom or mowing the lawn, than see ...
The disease develops as a complication or progression of either Epstein–Barr virus-positive infectious mononucleosis (EPV+ IM) or chronic active Epstein–Barr virus infection (CAEBV)., [1] that is, as a worsening of the signs/symptoms some three weeks after the onset of an EBV+ IM-like disease or an any time during the course of CAEBV.
How long do they last? Symptoms begin 12 to 48 hours after exposure to the virus and last for about 1 to 3 days. Even after recovering, infected individuals can be contagious for two more weeks.
It will generally not be positive during the 4–6 week incubation period before the onset of symptoms. The highest amount of heterophile antibodies occurs 2 to 5 weeks after the onset of symptoms. [9] If positive, it will remain so for at least six weeks. [10] An elevated heterophile antibody level may persist up to 1 year. [9]