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Most Pax genes contain a homeobox and a paired domain that also binds DNA to increase binding specificity, though some Pax genes have lost all or part of the homeobox sequence. [46] Pax genes function in embryo segmentation , nervous system development, generation of the frontal eye fields , skeletal development, and formation of face structures.
HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A, is a human gene on chromosome 12. [ 5 ] [ 6 ] [ 7 ] It is ubiquitously expressed in many tissues and cell types. [ 8 ] The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression ...
Homeobox protein Hox-A7 is a protein that in humans is encoded by the HOXA7 gene. [5] [6] [7] In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic ...
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17 . The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation .
Homeobox protein Hox-A9 is a protein that in humans is encoded by the HOXA9 gene. [5] [6] In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic ...
15438 Ensembl ENSG00000128709 ENSMUSG00000043342 UniProt P28356 P28357 RefSeq (mRNA) NM_014213 NM_013555 RefSeq (protein) NP_055028 NP_038583 Location (UCSC) Chr 2: 176.12 – 176.12 Mb Chr 2: 74.53 – 74.53 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-D9 is a protein that in humans is encoded by the HOXD9 gene. Function This gene belongs to the homeobox ...
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The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters , HOXA, HOXB, HOXC and HOXD, located on different chromosomes , consisting of 9 to 11 genes arranged in tandem.