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  2. Iron overload - Wikipedia

    en.wikipedia.org/wiki/Iron_overload

    However ferritin levels may be elevated due to a variety of other causes including obesity, infection, inflammation (as an acute phase protein), chronic alcohol intake, liver disease, kidney disease, and cancer. [7] [32] [33] In males and postmenopausal females, normal range of serum ferritin is between 12 and 300 ng/mL (670 pmol/L) .

  3. Hemochromatosis type 4 - Wikipedia

    en.wikipedia.org/wiki/Hemochromatosis_type_4

    More ferritin is produced to suppress oxidative cell damage, although the amount of ferritin that cells can accumulate is limited. [ 12 ] Hemochromatosis type 4B is characterized by abnormal iron release from macrophages and enterocytes because the mutant ferroportin is resistant to the hepcidin protein, which serves a regulatory function in ...

  4. Ferritin - Wikipedia

    en.wikipedia.org/wiki/Ferritin

    The ferritin levels measured usually have a direct correlation with the total amount of iron stored in the body. However, ferritin levels may be artificially high in cases of anemia of chronic disease, where ferritin is elevated in its capacity as an inflammatory acute phase protein and not as a marker for iron overload. [citation needed]

  5. 6 Reasons Why You Might Be Itching Down There - AOL

    www.aol.com/lifestyle/6-reasons-why-might...

    The good news: you probably don't need to panic.

  6. 11 things your itchy skin can reveal about your health - AOL

    www.aol.com/article/lifestyle/2018/06/06/11...

    From cancer to pregnancy, the possible causes of chronic itch go way beyond dry skin. ... 11 things your itchy skin can reveal about your health. Ashley Lewis. June 6, 2018 at 12:17 PM.

  7. Neuroferritinopathy - Wikipedia

    en.wikipedia.org/wiki/Neuroferritinopathy

    These oxidative molecules can cause oxidative brain damage. Iron that is bound to ferritin in nonreactive. [1] Fenton Reaction (1) Fe 2+ + H 2 O 2 → Fe 3+ + HO• + OH − (2) Fe 3+ + H 2 O 2 → Fe 2+ + HOO• + H + The ferritin protein is made up of heavy chain (H) and light chain (L) subunits. In neuroferritinopathy, the gene encoding the ...

  8. Hemosiderosis - Wikipedia

    en.wikipedia.org/wiki/Hemosiderosis

    Serum ferritin is a low cost, readily available, and minimally invasive method for assessing body iron stores. However, the major problem with using it as an indicator of hemosiderosis is that it can be elevated in a range of other medical conditions unrelated to iron levels including infection, inflammation, fever, liver disease, renal disease ...

  9. Human iron metabolism - Wikipedia

    en.wikipedia.org/wiki/Human_iron_metabolism

    Iron can be stored in ferritin as ferric iron due to the ferroxidase activity of the ferritin heavy chain. [28] Dysfunctional ferritin may accumulate as hemosiderin, which can be problematic in cases of iron overload. [29] The ferritin storage iron pool is much larger than the labile iron pool, ranging in concentration from 0.7 mM to 3.6 mM. [25]