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C = Concentration of the chemical in the contaminated environmental medium (soil or water) to which the person is exposed. The units are mg/kg for soil and mg/L for water. IR i = Intake rate of the contaminated environmental medium for age bin "i". The units are kg/day for soil and L/day for water. BW i = Body weight of the exposed person for ...
Population equivalent (PE) or unit per capita loading, or equivalent person (EP), is a parameter for characterizing industrial wastewaters.It essentially compares the polluting potential of an industry (in terms of biodegradable organic matter) with a population (or certain number of people), which would produce the same polluting load.
Cholinesterase inhibition was observed at all dose levels tested, and a NOAEL of 0.03 mg/kg/day estimated by dividing a LOAEL of 0.3 mg/kg/day by an uncertainty factor of 10. As with the acute RfD, the chronic RfD of 3×10 −4 mg/kg/day was determined by dividing this NOAEL by the inter- and intraspecies uncertainty factors.
In a healthy adult male of 75 kg (165 lb) with a blood volume of 5 L, a blood glucose level of 5.5 mmol/L (100 mg/dL) amounts to 5 g, equivalent to about a teaspoonful of sugar. [14] Part of the reason why this amount is so small is that, to maintain an influx of glucose into cells, enzymes modify glucose by adding phosphate or other groups to it.
Parts-per notations may be expressed in terms of any unit of the same measure. For instance, the expansion coefficient of some brass alloy, α = 18.7 ppm/°C, may be expressed as 18.7 (μm/m)/°C, or as 18.7 (μ in/in)/°C; the numeric value representing a relative proportion does not change with the adoption of a different unit of length.
In a 90-day study on dogs, in which the males received 6.9 mg/kg/day and the females 8.25 mg/kg/day, ataxia, emesis, miosis, and tremors were observed. Brain and erythrocyte acetylcholinesterase were inhibited (61-64% and 93-04%, respectively). At 0.71 mg/kg/day in male dogs, the reduction in brain acetylcholinesterase was 23%.
For methylmercury, the US Environmental Protection Agency (US EPA) has estimated a safe daily intake level of 0.1 μg/kg body weight per day. [ 19 ] The National Institute for Occupational Safety and Health (NIOSH) recommends that exposures to mercury metal be limited to an average of 0.05 mg/m 3 over a 10-hour workday in addition to a ceiling ...
An approximation of 0.3 g/kg/day divided into 4 equal spaced intervals has been suggested since creatine needs may vary based on body weight. [ 26 ] [ 20 ] It has also been shown that taking a lower dose of 3 grams a day for 28 days can also increase total muscle creatine storage to the same amount as the rapid loading dose of 20 g/day for 6 ...