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The midgut is the portion of the human embryo from which most of the intestines develop. After it bends around the superior mesenteric artery , it is called the "midgut loop". It comprises the portion of the alimentary canal from the end of the foregut at the opening of the bile duct to the hindgut , about two-thirds of the way through the ...
The midgut forms the primary intestinal loop, from which originates the distal duodenum to the entrance of the bile duct. The loop continues to the junction of the proximal two-thirds of the transverse colon with the distal third. At its apex, the primary loop remains temporarily in open connection with the yolk sac through the vitelline duct.
Intestinal malrotation is a congenital anomaly of rotation of the midgut. It occurs during the first trimester as the fetal gut undergoes a complex series of growth and development. Malrotation can lead to a dangerous complication called volvulus, in which cases emergency surgery is indicated. [1]
Due to intestinal malrotation 4.4% of children with omphalocele will experience a midgut volvulus in the days, months, or years after surgery. Parents of children with omphalocele should seek immediate medical attention if their child displays signs and symptoms of an intestinal obstruction at any point in their childhood to avoid the ...
During herniation, the midgut rotates 90° anti-clockwise around the axis of the SMA and forms the midgut loop. The cranial portion of the loop moves to the right and the caudal portion of the loop moves toward the left. This rotation occurs at about the eighth week of development.
In the human embryo, the vitelline duct, also known as the vitellointestinal duct, [1] the yolk stalk, [1] the omphaloenteric duct, [1] or the omphalomesenteric duct, [1] is a long narrow tube that joins the yolk sac to the midgut lumen of the developing fetus. [2]
This clinically manifests as poor feeding and bilious vomiting in neonates. Screening can be performed with an upper GI series. The most severe complication of malrotation is midgut volvulus, in which the mesenteric base twists around the superior mesenteric artery, compromising intestinal perfusion, leading to bowel necrosis.
The umbilical ring is a dense fibrous ring surrounding the umbilicus at birth. [1] At about the sixth week of embryological development, the midgut herniates through the umbilical ring; six weeks later it returns to the abdominal cavity and rotates around the superior mesenteric artery.