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Parvoviruses are among the smallest viruses (hence the name, from Latin parvus meaning small) and are 18–28 nm in diameter. [16] Parvoviruses can cause disease in some animals, including starfish and humans. Because the viruses require actively dividing cells to replicate, the type of tissue infected varies with the age of the animal.
[1] [2] It is one of only three known transmissible cancers in mammals; the others are devil facial tumor disease, a cancer which occurs in Tasmanian devils, and contagious reticulum cell sarcoma of the Syrian hamster. The tumor cells are themselves the infectious agents, and the tumors that form are not genetically related to the host dog. [3]
The attachment of polyomaviruses to host cells is mediated by the binding of VP1 to sialylated glycans on the cell surface. [2] [13] [16] [17] In some particular viruses, additional cell-surface interactions occur; for example, the JC virus is believed to require interaction with the 5HT2A receptor and the Merkel cell virus with heparan sulfate.
It was suggested that such types of viruses could cause cancer by introducing new genes into the genome. Genetic analysis of mice infected with Friend virus confirmed that retroviral integration could disrupt tumor suppressor genes, causing cancer. [51] Viral oncogenes were subsequently discovered and identified to cause cancer.
Feline foamy virus; Feline immunodeficiency virus; Feline infectious peritonitis; Feline leukemia virus; Carnivore protoparvovirus 1; Feline viral rhinotracheitis; Filoviridae; Foot-and-mouth disease; Foot-and-mouth disease virus; Fowlpox
Papillomaviridae is a family of non-enveloped DNA viruses whose members are known as papillomaviruses. [1] Several hundred species of papillomaviruses, traditionally referred to as "types", [2] have been identified infecting all carefully inspected mammals, [2] but also other vertebrates such as birds, snakes, turtles and fish.
SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans.Like other polyomaviruses, SV40 is a DNA virus that is found to cause tumors in humans and animals, but most often persists as a latent infection.
Herpesviruses also cause cancer in animals, especially leukemias and lymphomas. [13] Human T cell lymphotropic virus was the first human retrovirus discovered by Robert Gallo and colleagues at NIH. [20] The virus causes Adult T-cell leukemia, a disease first described by Takatsuki and colleagues in Japan [21] and other neurological diseases ...