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The most common use for azaperone is in relatively small doses as a "serenic" (to reduce aggression) in farmed pigs, either to stop them fighting or to encourage sows to accept piglets. Higher doses are used for anesthesia in combination with other drugs such as xylazine , tiletamine and zolazepam .
Piperazine is freely soluble in water and ethylene glycol, but insoluble in diethyl ether. It is a weak base with two pK b of 5.35 and 9.73 at 25 °C.; the pH of a 10% aqueous solution of piperazine is 10.8–11.8. Piperazine readily absorbs water and carbon dioxide from the air.
Benzylpiperazine (BZP) is a substance often used as a recreational drug and is known to have euphoriant and stimulant properties. Several studies conducted between 2000 and 2011 found that the effects of BZP are similar to amphetamine, although BZP's dosage is roughly 10 times higher by weight.
1-Phenylpiperazine (1-PP or PP) is a simple chemical compound and drug featuring a phenyl group bound to a piperazine ring. [1] The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class. [2] It is a rigid analogue of amphetamine.
Spanish fly isn’t just ineffective as an aphrodisiac — it’s also dangerous. So keep Spanish fly and other herbal aphrodisiacs at arm’s length. There’s just way too much at stake.
Unlike the related piperazine compound meta-chlorophenylpiperazine (mCPP), TFMPP has insignificant affinity for the 5-HT 3 receptor (IC 50 = 2,373 nM). [7] TFMPP also binds to the SERT (EC 50 = 121 nM) and evokes the release of serotonin. [6] It has no effects on dopamine or norepinephrine reuptake or efflux. [6]
Cinnarizine is an antihistamine and calcium channel blocker of the diphenylmethylpiperazine group. [5] It is prescribed for nausea and vomiting due to motion sickness [6] or other sources such as chemotherapy, [7] vertigo, [8] or Ménière's disease. [9]
1-(1-Naphthyl)piperazine (1-NP) is a drug which is a phenylpiperazine derivative. It acts as a non- selective , mixed serotonergic agent, exerting partial agonism at the 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , and 5-HT 1F receptors , [ 1 ] [ 2 ] [ 3 ] while antagonizing the 5-HT 2A , 5-HT 2B , and 5-HT 2C receptors .