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Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but which contains proteins and other constituents of whole blood in suspension. It makes up about 55% of the body's total blood volume. [1] It is the intravascular part of extracellular fluid (all body fluid outside cells).
Cerebral blood flow (CBF) is the blood supply to the brain in a given period of time. [8] In an adult, CBF is typically 750 millilitres per minute or 15.8 ± 5.7% of the cardiac output. [9] This equates to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute. [10] [11] [12]
Although the human brain represents only 2% of the body weight, it receives 15% of the cardiac output, 20% of total body oxygen consumption, and 25% of total body glucose utilization. [138] The brain mostly uses glucose for energy, and deprivation of glucose, as can happen in hypoglycemia , can result in loss of consciousness. [ 139 ]
The combined surface area of all red blood cells of the human body would be roughly 2,000 times as great as the body's exterior surface. [ 14 ] 4,000–11,000 leukocytes : [ 15 ] White blood cells are part of the body's immune system ; they destroy and remove old or aberrant cells and cellular debris, as well as attack infectious agents ...
Consciousness functionally can be divided into two components: (i) wakefulness, which is arousal and alertness; (ii) content of consciousness, which is the processing of content. A study of traumatic brain injuries in war veterans was undertaken to better understand the functional role of the claustrum.
Research on microplastics in the body is still new, and whether these microscopic bits of plastic can pass through the blood-brain barrier in humans is still a big question.
Circumventricular organs (CVOs) (circum-: around ; ventricular: of ventricle) are structures in the brain characterized by their extensive and highly permeable capillaries, unlike those in the rest of the brain where there exists a blood–brain barrier (BBB) at the capillary level.
Phosphatidylserine (PS) is the major acidic phospholipid class that accounts for 13–15% of the phospholipids in the human cerebral cortex. [7] In the plasma membrane, PS is localized exclusively in the cytoplasmic leaflet where it forms part of protein docking sites necessary for the activation of several key signaling pathways.