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Of the platinum compounds, research has shown cisplatin to be the most frequently involved in peripheral neuropathy. [3] 2) Taxanes, including paclitaxel (and protein-bound pactiltaxel e.g. abraxane), docetaxel, and cabazitaxel, are used to treat ovarian, breast, non-small cell lung, and prostate cancers. [3]
Macmillan Cancer Support merged with cancer information charity Cancerbackup in 2008. Macmillan works in partnership with other cancer research organisations and is a partner of the National Cancer Research Institute. Macmillan is part of the Richmond Group of Charities, which is a coalition of 14 leading health and social care organisations in ...
Cisplatin is a chemical compound with formula cis-[Pt(NH 3) 2 Cl 2]. It is a coordination complex of platinum that is used as a chemotherapy medication used to treat a number of cancers . [ 3 ] These include testicular cancer , ovarian cancer , cervical cancer , bladder cancer , head and neck cancer , esophageal cancer , lung cancer ...
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations.In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy.
Most major toxicities of cisplatin, especially nephrotoxicity, were also reduced in the group of patients treated with lipoplatin and treatment did not require hospitalisation for lipoplatin patients. Median survival times were 10 months for the lipoplatin arm and 8 months for the cisplatin arm, with a ‘’p’’-value of 0.155.
A chemo-protective agent [1] is any drug that helps to reduce the side- effects of chemotherapy.These agents protect specific body parts from harmful anti-cancer treatments that could potentially cause permanent damage to important bodily tissues.
Netupitant is a selective NK 1 receptor antagonist. [6]Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the activity of the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which ...
Irinotecan, sold under the brand name Camptosar among others, is an anti-cancer medication used to treat colon cancer and small cell lung cancer. [8] For colon cancer it is used either alone or with fluorouracil. [8]