Search results
Results from the WOW.Com Content Network
It has very low affinity for human serum sex hormone-binding globulin (SHBG), about 10% of that of testosterone and 2% of that of DHT. [25] The drug is metabolized in the liver by 6β- hydroxylation , 3α- and 3β- oxidation , 5β-reduction , 17- epimerization , and conjugation among other reactions . [ 24 ]
Starvation response in animals (including humans) is a set of adaptive biochemical and physiological changes, triggered by lack of food or extreme weight loss, in which the body seeks to conserve energy by reducing metabolic rate and/or non-resting energy expenditure to prolong survival and preserve body fat and lean mass.
Perioperative mortality has been defined as any death, regardless of cause, occurring within 30 days after surgery in or out of the hospital. [1] Globally, 4.2 million people are estimated to die within 30 days of surgery each year. [2]
An infectious disease agent can be transmitted in two ways: as horizontal disease agent transmission from one individual to another in the same generation (peers in the same age group) [3] by either direct contact (licking, touching, biting), or indirect contact through air – cough or sneeze (vectors or fomites that allow the transmission of the agent causing the disease without physical ...
The Child-Pugh score is a validated predictor of mortality after a major surgery. [102] For example, Child class A patients have a 10% mortality rate and Child class B patients have a 30% mortality rate while Child class C patients have a 70–80% mortality rate after abdominal surgery. [ 102 ]
[citation needed] At the time, this represented a unique dissociation of anabolic from androgenic effects after oral administration. [ clarification needed ] [ 2 ] The product was introduced for clinical use in 1965 and remained in use until 1994, when production was discontinued.
Sepsis will prove fatal in approximately 24.4% of people, and septic shock will prove fatal in 34.7% of people within 30 days (32.2% and 38.5% after 90 days). [105] Lactate is a useful method of determining prognosis, with those who have a level greater than 4 mmol/L having a mortality of 40% and those with a level of less than 2 mmol/L having ...
Treatment courses are a minimum of 18 months and may last years; it may require surgery, though death rates remain high despite optimal treatment. That said, good outcomes are still possible. Treatment courses that are at least 18 months long and which have a directly observed component can increase cure rates to 69%.