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Paliperidone, sold under the brand name Invega among others, is an atypical antipsychotic. [14] It is indicated in the treatment of schizophrenia and schizoaffective disorder . [ 14 ] It is marketed by J&J Innovative Medicine
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
The side effects reportedly associated with the various atypical antipsychotics vary and are medication-specific. ... Invega Sustenna: Atypical: Water a: 39–819 mg ...
J&J sold more than $4.1 billion worth of Invega Sustenna and related drugs worldwide last year, with nearly $2.9 billion in U.S. sales, according to a company report.
more extrapyramidal side effects (EPS) and less antihistaminic effects (e.g. sedation), alpha adrenergic antagonism (e.g. orthostatic hypotension), and anticholinergic effects (e.g. dry mouth) middle: perphenazine and loxapine: intermediate D2 affinity, with more off-target effects than high-potency agents low: chlorpromazine
Think about mental health and the impact of our Invega portfolio, Spravato, and the potential of the Intra-Cellular Therapies acquisition we announced last week. ... avoiding those side effects ...
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Invega (paliperidone) – atypical antipsychotic used to treat schizophrenia and schizoaffective disorder; K. Keppra (levetiracetam) – an anticonvulsant drug which ...