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It can be caused by certain drug interactions, as well as drinking alcohol while taking a medication like Lexapro. The signs and symptoms of Serotonin Syndrome include: Agitation or restlessness ...
Escitalopram, sold under the brand names Lexapro and Cipralex, among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class. [9] It is mainly used to treat major depressive disorder and generalized anxiety disorder . [ 9 ]
[187] [188] Fluvoxamine is an agonist of the σ 1 receptor, while sertraline is an antagonist of the σ 1 receptor, and paroxetine does not significantly interact with the σ 1 receptor. [187] [188] None of the SSRIs have significant affinity for the σ 2 receptor. [187] [188] Fluvoxamine has by far the strongest activity of the SSRIs at the σ ...
Trazodone, sold under many brand names, [1] is an antidepressant medication [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.
Lexapro on its own, at FDA-approved dosages, is unlikely to cause serotonin syndrome, but certain drug interactions can increase your serotonin levels and therefore, your risk of serotonin syndrome.
To avoid drug interactions, your healthcare provider will tell you which process to use and how to switch from one antidepressant to another safely based on your medications and overall health.
This interaction seems to be critical for increased availability of norepinephrine in or near the synaptic clefts. Actions of imipramine-like tricyclic antidepressants have complex, secondary adaptions to their initial and sustained actions as inhibitors of norepinephrine transport and variable blockade of serotonin transport.
Lexapro (escitalopram) – an antidepressant of the SSRI class; Librium (chlordiazepoxide) – a benzodiazepine used to treat acute alcohol withdrawal; Lithobid, Eskalith – a mood stabilizer; Loxam (escitalopram) – an antidepressant of the SSRI class; Lunesta (eszopiclone) – a non-benzodiazepine hypnotic