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Believed to be the first coupon ever, this ticket for a free glass of Coca-Cola was first distributed in 1888 to help promote the drink. By 1913, the company had redeemed 8.5 million tickets. [6] Coca-Cola's 1888-issued "free glass of" is the earliest documented coupon. [6] [7] Coupons were mailed to potential customers and placed in magazines ...
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[37] [35] In affected men, semen volume is decreased an average of 30%, [38] with a smaller subgroup of patients also experiencing a decrease of sperm motility of 6 to 12%. [39] [40] Sperm shape and function are unaffected and the impact on male fertility is unknown. [41] These negative effects reverse by 3–4 months after discontinuation of ...
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The Bristol-Myers Squibb Company, doing business as Bristol Myers Squibb (BMS), is an American multinational pharmaceutical company.Headquartered in Princeton, New Jersey, [2] BMS is one of the world's largest pharmaceutical companies and consistently ranks on the Fortune 500 list of the largest U.S. corporations.
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
Zero coupon bonds have a duration equal to the bond's time to maturity, which makes them sensitive to any changes in the interest rates. Investment banks or dealers may separate coupons from the principal of coupon bonds, which is known as the residue, so that different investors may receive the principal and each of the coupon payments.