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Darier's disease (DD) is a rare, genetic skin disorder. It is an autosomal dominant disorder, that is, if one parent has DD, there is a 50% chance than a child will inherit DD. It was first reported by French dermatologist Ferdinand-Jean Darier in 1889. Mild forms of the disease are the most common, consisting of skin rashes that flare up under ...
Keratosis pilaris. Keratosis pilaris ( KP; also follicular keratosis, lichen pilaris, or colloquially chicken skin[ 1]) is a common, autosomal - dominant, genetic condition of the skin's hair follicles characterized by the appearance of possibly itchy, small, gooseflesh -like bumps, with varying degrees of reddening or inflammation. [ 2]
Epidermodysplasia verruciformis ( EV) is a skin condition characterised by warty skin lesions. [ 1] It results from an abnormal susceptibility to HPV infection (HPV) and is associated with a high lifetime risk of squamous cell carcinomas in skin. [ 1] It generally presents with scaly spots and small bumps particularly on the hands, feet, face ...
Cold urticaria (essentially meaning cold hives) is a disorder in which large red welts called hives ( urticaria) form on the skin after exposure to a cold stimulus. [ 1] The hives are usually itchy and often the hands and feet will become itchy and swollen as well. Hives vary in size from about 7 mm in diameter to as big as about 27 mm or larger.
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [4] [5] These areas are red, pink, or purple, dry, itchy, and scaly.[8] [3] Psoriasis varies in severity from small localized patches to complete body coverage. [3]
Palmoplantar keratoderma and spastic paraplegia (also known as "Charcot–Marie–Tooth disease with palmoplantar keratoderma and nail dystrophy" [ 1]) is an autosomal dominant or x-linked dominant condition that begins in early childhood with thick focal keratoderma over the soles and, to a lesser extent, the palms. [ 1]: 513.
In people with Cushing syndrome, “too much cortisol leads to a more rounded face, pinkish red cheeks, thinner skin with easy bruises, a puffy neck, and a worsening upper back hump,” Dr. Ghalib ...
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