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Diazepam does not possess any chiral centers in its structure, but it does have two conformers. The two conformers mentioned were the 'P'-conformer and 'M'-conformer. Diazepam is an equimolar mixture and it was shown through CD spectra in serum protein solutions, that the 'P'-conformer is preferred by α1-acid glycoprotein binding.
Chlordiazepoxide. Chlordiazepoxide, trade name Librium among others, is a sedative and hypnotic medication of the benzodiazepine class; it is used to treat anxiety, insomnia and symptoms of withdrawal from alcohol, benzodiazepines, and other drugs. Chlordiazepoxide has a medium to long half-life but its active metabolite has a very long half-life.
Prazepam. Prazepam is a benzodiazepine derivative drug developed by Warner-Lambert in the 1960s. [ 2] It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. [ 3] Prazepam is a prodrug for desmethyldiazepam which is responsible for the therapeutic effects of prazepam.
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The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses. The elimination half-life is how long it takes for half ...
Benzodiazepines ( BZD, BDZ, BZs ), colloquially called " benzos ", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, insomnia, and seizures. The first benzodiazepine, chlordiazepoxide (Librium), was discovered ...
Older Americans are having little success getting prescriptions for weight-loss drug Wegovy covered by Medicare despite the federal healthcare program's decision to pay for patients with obesity ...
New Mexico’s attorney general is investigating Memorial Medical Center of Las Cruces to determine if the facility, highlighted in a recent NBC News report, violated state laws by turning away ...