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Smoking, diabetes, chronic pancreatitis or inflammation of the pancreas, family history of pancreatic cancer, and certain genetic syndromes are all known risk factors. Carrying extra weight that is unhealthy for your body may also be a contributing factor.
The cause of most pancreatic cancers is unclear. Doctors have identified some factors that may increase the risk of pancreatic cancer, including smoking, diabetes, chronic inflammation of the pancreas (pancreatitis), obesity, and family history, but the cause is not clear.
Pancreas cancer. Injuries from trauma or surgery. Conditions that can lead to chronic pancreatitis include: Damage from repeated acute pancreatitis. Heavy alcohol use. Inherited genes linked to pancreatitis. High triglyceride levels in the blood. High calcium levels in the blood. Sometimes, a cause for pancreatitis is never found.
There are some risk factors associated with pancreatic cancer, like smoking and obesity. Those are both modifiable risk factors. So the healthier you are, the less risk you might have of pancreatic cancer. But ultimately if you have a pancreas, there's always a risk of developing pancreatic cancer.
For most people diagnosed with pancreatic cancer, there is no obvious predilection, but there are some known risk factors. Smoking is one of the most common to be strongly associated with pancreatic cancer risk. There also is an association between pancreatic cancer and diabetes.
Mayo Clinic researchers studying pancreatic cancer — the third deadliest form of cancer in the U.S. — recently made a discovery that advances knowledge of how metastasis unfolds. They identified a cell-signaling protein that drives pancreatic cancer cell growth that could be a potential therapeutic target.
In the study, which was published in Clinical and Translational Gastroenterology, nearly 1 in 6 people diagnosed with pancreatic cancer were found to have an inherited cancer-related gene mutation that likely predisposed them to the disease.
Autoimmune pancreatitis, also called AIP, is difficult to diagnose. Often, it doesn't cause any symptoms. Symptoms of type 1 AIP are like those of pancreatic cancer. Pancreatic cancer symptoms can include: Dark urine. Pale stools or stools that float in the toilet. Yellow skin and eyes, called jaundice. Pain in your upper belly or middle part ...
Most pancreatic cysts are benign, but some types are cancerous. Find out about symptoms, causes and treatment of cysts in the pancreas.
Causes. Pancreatic neuroendocrine tumors happen when cells in the pancreas develop changes in their DNA. A cell's DNA holds the instructions that tell the cell what to do. The changes, which doctors call mutations, tell the cells to multiply quickly.