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Low LDL cholesterol, which is less common, is also known as hypolipidemia (low cholesterol). ... Cardiovascular diseases — such as stroke, coronary artery disease, peripheral artery disease ...
“High levels of [harmful] LDL cholesterol can lead to plaque buildup in the arteries, increasing the risk of heart disease and stroke,” says Wendy Bazilian, Dr.P.H., M.A., RDN, a registered ...
In contrast, no evidence was found for a link with hemorrhagic stroke (although higher cholesterol levels conferred a relative protection), and neither did statin drugs worsen the risk. [4] The Heart Protection Study found no increase in either respiratory disease or neuropsychiatric illness in a large trial population taking a statin drug. [5]
In addition to plaque formation, LDL-C molecules can undergo oxidation. [1] Oxidation can cause further accumulation of cholesterol and the release of inflammatory cytokines, which damages the blood vessels. [1] [7] Due to the damaging effects of LDL-C, high levels increase the risk for cardiovascular disease and indicate dyslipidemia. [1]
The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP). JUPITER was the first clinical trial to indicate that statin therapy may provide benefit to patients with low-to-normal LDL levels and no known cardiovascular disease.
High cholesterol: In particular, elevated LDL (low-density lipoprotein) cholesterol can build up your arteries, increasing your stroke risk. Heart disease: ...
Low-density lipoprotein (LDL) cholesterol — aka the “bad” cholesterol ... Dyslipidemia can increase your risk of: ... Inflammation. Cardiovascular diseases — such as stroke, coronary ...
A systematic review found it brought lower total cholesterol of 12.3% to 31.3% and lower LDL of 7.6% to 40.8%. “It seems to have some effect on decreasing cholesterol, but the research is not as ...
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