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Atrophic gastritis under low power. H&E stain. Autoimmune metaplastic atrophic gastritis (AMAG) is an inherited form of atrophic gastritis characterized by an immune response directed toward parietal cells and intrinsic factor. [6] Achlorhydria induces G cell (gastrin-producing) hyperplasia, which leads to hypergastrinemia.
Gastritis is the inflammation of the lining of the stomach. [1] ... (atrophic gastritis) and are progressively replaced by mucous glands. Gastric ulcers may develop ...
Inflammation of the stomach by infection from any cause is called gastritis, and when including other parts of the gastrointestinal tract called gastroenteritis. When gastritis persists in a chronic state, it is associated with several diseases, including atrophic gastritis, pyloric stenosis, and gastric cancer.
PA may be considered as an end stage of autoimmune atrophic gastritis, a disease characterised by stomach atrophy and the presence of antibodies to parietal cells and intrinsic factor. [38] [39] Autoimmune atrophic gastritis, is localised to the body of the stomach, where parietal cells are located. [36]
Stomach diseases include gastritis, gastroparesis, Crohn's disease and various cancers. [1] The stomach is an important organ in the body. It plays a vital role in digestion of foods, releases various enzymes and also protects the lower intestine from harmful organisms. The stomach connects to the esophagus above and to the small intestine below.
A greater cytotoxicity will result in the change from a non-atrophic gastritis to an atrophic gastritis, with the loss of mucous glands. This condition is a prequel to the development of peptic ulcers and gastric adenocarcinoma. [149] Eradication of H. pylori is recommended to treat the infection, including when advanced to peptic ulcer disease.
Reactive gastropathy is morphologically distinct entity [3] [4] that can be separated from gastritis, which by definition has a significant inflammatory component. As a reactive gastropathy may mimic a (true) gastritis symptomatically and visually in an endoscopic examination , it may incorrectly be referred to as a gastritis.
This syndrome defines the association between thyroid disease and chronic gastritis, which was first described in the 1960s. [43] This term was coined also to indicate the presence of thyroid autoantibodies or autoimmune thyroid disease in patients with pernicious anemia, a late clinical stage of atrophic gastritis. [44]
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