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Possible adverse effects of tibolone include unscheduled vaginal bleeding (OR Tooltip Odds ratio = 2.79; incidence 13–26% more than placebo), an increased risk of breast cancer in women with a history of breast cancer (OR Tooltip Odds ratio = 1.5) although apparently not without a history of breast cancer (OR Tooltip Odds ratio = 0.52), an ...
Intermenstrual bleeding (IMB), or metrorrhagia, is vaginal bleeding at irregular intervals between expected menstrual periods. [1] It may be associated with bleeding with sexual intercourse . [ 2 ] The term metrorrhagia, in which metro means measure and -rrhagia means abnormal flow, [ 3 ] is no longer recommended.
Hormone therapy for treatment of menopausal symptoms can also cause abnormal bleeding. Unscheduled bleeding that occurs during such hormonal treatment is termed "breakthrough bleeding" (BTB) Breakthrough bleeding may result from inconsistent use of hormonal treatment, although in the initial months after initiation of a method, it may occur ...
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Pelvic pain (along with abnormal bleeding and brown discharge) is a symptom of cervical cancer. If you're experiencing these symptoms and haven't had a Pap smear in the past year, talk to your doc.
Hormonal therapies to reduce or stop menstrual bleeding have long been used to manage a number of gynecologic conditions including menstrual cramps (dysmenorrhea), heavy menstrual bleeding, irregular or other abnormal uterine bleeding, menstrual-related mood changes (premenstrual syndrome or premenstrual dysphoric disorder), and pelvic pain due to endometriosis or uterine fibroids.
In the first few months of extended or continuous use of combined oral contraceptives, unscheduled bleeding or spotting may occur. [82] However, the bleeding or spotting is expected to resolve after a few months of use. [82] Menstrual suppression is commonly used for convenience especially when women go on vacation. [79]
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