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Influenza A viruses are further classified, based on the viral surface proteins hemagglutinin (HA or H) and neuraminidase (NA or N). 18 HA subtypes (or serotypes) and 11 NA subtypes of influenza A virus have been isolated in nature. Among these, the HA subtype 1-16 and NA subtype 1-9 are found in wild waterfowl and shorebirds and the HA ...
The subtypes of influenza A virus are estimated to have diverged 2,000 years ago. Influenza viruses A and B are estimated to have diverged from a single ancestor around 4,000 years ago, while the ancestor of influenza viruses A and B and the ancestor of influenza virus C are estimated to have diverged from a common ancestor around 8,000 years ago.
The project makes all sequence data publicly available through GenBank, an international, NIH-funded, searchable online database.This research helps to provide international researchers with the information needed to develop new vaccines, therapies and diagnostics, as well as improve understanding of the overall molecular evolution of Influenza and other genetic factors that determine their ...
Influenza A virus and influenza B virus circulate in humans and cause seasonal epidemics, and influenza C virus causes a mild infection, primarily in children. Influenza D virus can infect humans but is not known to cause illness. In humans, influenza viruses are primarily transmitted through respiratory droplets from
The Influenza Research Database (IRD) [1] [2] [3] is an integrative and comprehensive publicly available database and analysis resource to search, analyze, visualize, save and share data for influenza virus research.
Pigs can harbor influenza viruses adapted to humans and others that are adapted to birds, allowing the viruses to exchange genes and create a pandemic strain. A 2007 study reported: "In swine, three influenza A virus subtypes (H1N1, H3N2, and H1N2) are circulating throughout the world. In the United States, the classic H1N1 subtype was ...
Children, however, had their lowest flu vaccination rate in the past six seasons. By comparison, more than half of children (53.1%) had been vaccinated by that week in the 2019–20 season.
To unambiguously describe a specific isolate of virus, researchers use the Influenza virus nomenclature, [21] which describes, among other things, the subtype, year, and place of collection. Some examples include: [22] A/Rio de Janeiro/62434/2021 (H3N2). [22] The starting A indicates that the virus is an influenza A virus.
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