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Arterial occlusion is a condition involving partial or complete blockage of blood flow through an artery. Arteries are blood vessels that carry oxygenated blood to body tissues. [ 1 ] [ 2 ] An occlusion of arteries disrupts oxygen and blood supply to tissues, leading to ischemia . [ 1 ]
A coronary occlusion, or coronary artery disease, is the partial or complete obstruction of blood flow in a coronary artery. This condition was first discussed in 1910 by Sir William Osler . [ 1 ] This condition slows or blocks the supply of oxygen-rich blood to the heart . [ 2 ]
If blood flow through the coronary arteries is stopped completely, cardiac muscle cells may die, known as a myocardial infarction, or heart attack. [9] Coronary artery disease (CAD) is the most common cause of coronary ischemia. [7] Coronary ischemia and coronary artery disease are contributors to the development of heart failure over time. [10]
In the blood supply of the heart, the right coronary artery (RCA) is an artery originating above the right cusp of the aortic valve, at the right aortic sinus in the heart. [ 1 ] [ 2 ] It travels down the right coronary sulcus , towards the crux of the heart .
The left coronary artery arises from the aorta within the left cusp of the aortic valve and feeds blood to the left side of the heart. It branches into two arteries, the left anterior descending and the left circumflex. The left anterior descending artery perfuses the interventricular septum and anterior wall of the left ventricle. The left ...
Within ninety seconds of occlusion, the pressure gradient between the segment of the coronary vessel distal to the occlusion and the incipient collateral vessel precipitates damage to the internal elastic lamina, provoking an inflammatory response; monocytes and polycytes migrate to the vascular wall, which has, as a result of the occlusion ...
Coronary arteries are vessels supplying blood and nutrients to the heart muscle (). [1]Coronary arteries arise from ostia, openings of the aorta (the largest artery in the human body) at the upper third or middle third of the sinuses of Valsalva (the first part of the big pipe coming off the main pumping chamber).
Coronary angiography of a critical sub-occlusion of the common trunk of the left coronary artery and the circumflex artery. (See arrows) During coronary catheterization (often referred to as a "cath" or "cardiac cath" by physicians), blood pressures are recorded and fluoroscopy ( X-ray motion picture ) shadow-grams of the blood inside the ...