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As described in Biomaterials for In Situ Tissue Regeneration: A Review (Abdulghani & Mitchell, 2019), [27] in situ muscle tissue engineering requires very specific biomaterials which have the capability to recruit stem cells or progenitor cells to the site of the muscle defect, thus allowing regeneration of tissue without implantation of seed ...
Myosatellite cells contribute the most to muscle regeneration and repair. [23] This makes them a prime target for the meat culturing field. These satellite cells are the main source of most muscle cell formation postnatally, with embryonic myoblasts being responsible for prenatal muscle generation.
The cells underneath this cap then begin to rapidly divide and form a cone shaped end to the amputation known as a blastema. Included in the blastema are skin, muscle, and cartilage cells that de-differentiate and become similar to stem cells in that they can become multiple types of cells.
They are crucial for the repair of muscle, but have a very limited ability to replicate. Activated by stimuli such as injury or high mechanical load, satellite cells are required for muscle regeneration in adult organisms. [4] In addition, satellite cells have the capability to also differentiate into bone or fat. In this way, satellite cells ...
Immune system contribution to regeneration of tissues generally involves specific cellular components, transcription of a wide variety of genes, morphogenesis, epithelia renewal and proliferation of damaged cell types (progenitor or tissue-resident stem cells). However, current knowledge reveals more and more studies about immune system ...
Smooth muscle is grouped into two types: single-unit smooth muscle, also known as visceral smooth muscle, and multiunit smooth muscle. Most smooth muscle is of the single-unit type, and is found in the walls of most internal organs (viscera); and lines blood vessels (except large elastic arteries), the urinary tract , and the digestive tract .
Compensatory hyperplasia permits tissue and organ regeneration. It is common in epithelial cells of the epidermis and intestine, liver hepatocytes, bone marrow cells, and fibroblasts. It occurs to a lesser extent in bone, cartilage, and smooth muscle cells. Hormonal hyperplasia occurs mainly in organs that depend on estrogen. For example, the ...
Permanent cells are cells that are incapable of regeneration. These cells are considered to be terminally differentiated and non-proliferative in postnatal life. This includes neurons , heart cells , skeletal muscle cells [ 1 ] and red blood cells . [ 2 ]