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The prevalence of fibromyalgia in gastrointestinal disease has been described mostly for celiac disease [53] and irritable bowel syndrome (IBS). [ 53 ] [ 51 ] IBS and fibromyalgia share similar pathogenic mechanisms, involving immune system mast cells , inflammatory biomarkers, hormones , and neurotransmitters such as serotonin .
Elastosis is the buildup of elastic fibers in tissues, and is a form of degenerative disease. [17] There are a multitude of causes, but the most commons cause is actinic elastosis of the skin, also known as solar elastosis , which is caused by prolonged and excessive sun exposure, a process known as photoaging .
Small fiber peripheral neuropathy is a type of peripheral neuropathy that occurs from damage to the small unmyelinated and myelinated peripheral nerve fibers. These fibers, categorized as C fibers and small Aδ fibers , are present in skin , peripheral nerves , and organs. [ 1 ]
To date, 37 human proteins have been found to form amyloid in pathology and be associated with well-defined diseases. [2] The International Society of Amyloidosis classifies amyloid fibrils and their associated diseases based upon associated proteins (for example ATTR is the group of diseases and associated fibrils formed by TTR). [3]
Leukodystrophies affect the growth and/or development of myelin, the fatty covering which acts as an insulator around nerve fibers throughout the central and peripheral nervous systems. MLD involves cerebroside sulfate accumulation. [1] [2] Metachromatic leukodystrophy, like most enzyme deficiencies, has an autosomal recessive inheritance ...
Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction. Mitochondria are the organelles that generate energy for the cell and are found in every cell of the human body except red blood cells .
Dietary fiber (fibre in Commonwealth English) or roughage is the portion of plant-derived food that cannot be completely broken down by human digestive enzymes. [1] Dietary fibers are diverse in chemical composition and can be grouped generally by their solubility, viscosity and fermentability which affect how fibers are processed in the body. [2]
This type of connective tissue is found mostly in the reticular layer (or deep layer) of the dermis. [3] It is also in the sclera and in the deeper skin layers. Due to high portions of collagenous fibers, dense irregular connective tissue provides strength, making the skin resistant to tearing by stretching forces from different directions.