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  2. Ventilation–perfusion coupling - Wikipedia

    en.wikipedia.org/wiki/Ventilation–perfusion...

    Smoking (long-term exposure to chemical irritants) can cause COPD, increasing the risk of lung cancer and heart disease. [14] Asthma is a common inflammatory disease causing the airway to swell and disturb breathing and ventilation(low V/A ratio). The cause is unrevealed, but allergens such as pollen, mold, respiratory infections, and air ...

  3. Bronchoconstriction - Wikipedia

    en.wikipedia.org/wiki/Bronchoconstriction

    The most common cause of emphysema is smoking and smoking cessation is mandatory if this incurable disease is to be treated. Prevention of bronchoconstriction by this pathway is vital for people with emphysema and there are several anticholinergic medications that in combination with mucous thinning agents such as Guaifenesin cause significant ...

  4. Acute severe asthma - Wikipedia

    en.wikipedia.org/wiki/Acute_severe_asthma

    In acute severe asthma, breathlessness may be so severe that it is impossible to speak more than a few words (inability to complete sentences). [5] [6] On examination, the respiratory rate may be elevated (more than 25 breaths per minute), and the heart rate may be rapid (110 beats per minute or faster). Reduced oxygen saturation levels (but ...

  5. Pathophysiology of asthma - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_asthma

    During an asthma episode, inflamed airways react to environmental triggers such as smoke, dust, or pollen. The airways narrow and produce excess mucus, making it difficult to breathe. In essence, asthma is the result of an immune response in the bronchial airways. [3]

  6. Dynamic hyperinflation - Wikipedia

    en.wikipedia.org/wiki/Dynamic_hyperinflation

    Dynamic hyperinflation is a phenomenon that occurs when a new breath begins before the lung has reached the static equilibrium volume. [1] In simpler terms, this means that a new breath starts before the usual amount of air has been breathed out, leading to a build-up of air in the lungs, and causing breathing in and out to take place when the lung is nearly full.

  7. Transpulmonary pressure - Wikipedia

    en.wikipedia.org/wiki/Transpulmonary_pressure

    The alveolar pressure is estimated by measuring the pressure in the airways while holding one's breath. [2] The intrapleural pressure is estimated by measuring the pressure inside a balloon placed in the esophagus. [2] Measurement of transpulmonary pressure assists in spirometry in availing for calculation of static lung compliance.

  8. Vaping — Even Without Nicotine — Has an Immediate Negative ...

    www.aol.com/vaping-even-without-nicotine...

    The study found that like cigarette users, decreased venous oxygen saturation — a decrease in “the amount of oxygen in the blood that returns to the heart after supplying oxygen to the body ...

  9. Work of breathing - Wikipedia

    en.wikipedia.org/wiki/Work_of_breathing

    The normal relaxed state of the lung and chest is partially empty. Further exhalation requires muscular work. Inhalation is an active process requiring work. [4] Some of this work is to overcome frictional resistance to flow, and part is used to deform elastic tissues, and is stored as potential energy, which is recovered during the passive process of exhalation, Tidal breathing is breathing ...

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