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Cholestene has been used as a dietary supplement and is often sold with red yeast rice to promote cholesterol management. However, these products contain a hidden drug ingredient, lovastatin, that may cause serious side effects when combined with other medications, such as muscle injury. [4]
Thermal alteration can also cause loss of the alkane side-chain at C 17. [13] An experiment demonstrated that over 4 weeks at 300 °C, cholestane underwent 17% decomposition of its alkane side chain. In contrast, the polycyclic structure (C 1-17) is very thermally stable. Diagenetic processes can also cause methyl shifts and aromatization.
Common side effects of the injectable form include kidney problems and neurological problems. [8] Other serious side effects may include anaphylaxis, muscle weakness, and Clostridioides difficile-associated diarrhea. [8] The inhaled form may result in constriction of the bronchioles. [8] It is unclear if use during pregnancy is safe for the ...
Effects of anticholinergic drugs include: Delirium (often with hallucinations and delusions indistinguishable from reality); Ocular symptoms (from eye drops): mydriasis, pupil dilation, and acute angle-closure glaucoma in those with shallow anterior chamber [11] [12] [13]
Citicoline may have neuroprotective effects due to its preservation of cardiolipin and sphingomyelin, preservation of arachidonic acid content of phosphatidylcholine and phosphatidylethanolamine, partial restoration of phosphatidylcholine levels, and stimulation of glutathione synthesis and glutathione reductase activity.
This crisis may be masked by the concomitant use of atropine along with cholinesterase inhibitor medication in order to prevent side effects. Flaccid paralysis resulting from cholinergic crisis can be distinguished from myasthenia gravis by the use of the drug edrophonium (Tensilon), as it only worsens the paralysis caused by cholinergic crisis ...
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Acetylcholine Acetylcholinesterase Acetylcholinesterase inhibition. Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, [1] inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, [2] thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ...
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