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Respiratory failure is classified as either Type 1 or Type 2, based on whether there is a high carbon dioxide level, and can be acute or chronic. In clinical trials, the definition of respiratory failure usually includes increased respiratory rate, abnormal blood gases (hypoxemia, hypercapnia, or both), and evidence of increased work of breathing.
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production and/or exacerbations) due to abnormalities of the airways (bronchitis ...
Due to the chronic nature of this disease, the leading symptom of restrictive lung disease is progressive exertional dyspnea. [3] For acute on chronic cases, shortness of breath , cough , and respiratory failure are some of the more common signs.
Chronic respiratory diseases are long-term diseases of the airways and other structures of the lung. They are characterized by a high inflammatory cell recruitment ( neutrophil ) and/or destructive cycle of infection , (e.g. mediated by Pseudomonas aeruginosa ).
Obstructive lung disease is a category of respiratory disease characterized by airway obstruction.Many obstructive diseases of the lung result from narrowing (obstruction) of the smaller bronchi and larger bronchioles, often because of excessive contraction of the smooth muscle itself.
The definition of a COPD exacerbation is commonly described as "lost in translation", [9] meaning that there is no universally accepted standard with regard to defining an acute exacerbation of COPD. Many organizations consider it a priority to create such a standard, as it would be a major step forward in the diagnosis and quality of treatment ...
Acute hypercapnia is called acute hypercapnic respiratory failure (AHRF) and is a medical emergency as it generally occurs in the context of acute illness. Chronic hypercapnia, where metabolic compensation is usually present, may cause symptoms but is not generally an emergency.
The term respiratory compromise is used to describe various intensities of respiratory dysfunction that can range from a chronic state of respiratory insufficiency to conditions that require emergency resuscitation and a breathing machine. [citation needed] Risk factors include a variety of substances, conditions, and environments: [5]
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