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Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
More than 40 percent of American adults struggle with obesity, and many are turning to weight loss pills. Obesity is associated with an increased risk of chronic health conditions like type 2 ...
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According to the Obesity Action Coalition, medications that may cause weight gain include: Anti-depressants: SSRIs such as Paxil, Zoloft, Celexa, and Prozac, and tricyclic antidepressants
Obesity is a growing pandemic for many industrialized nations, especially in the U.S., where it now affects almost 36% of adults and 17% of adolescents. As with any sweeping problem, there are ...
Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
The FDA conducted two studies, both of which found that Zepbound helps reduce sleep apnea symptoms in some patients by aiding weight loss. Both studies monitored obese adults with moderate to ...
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