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Francisella tularensis is a pathogenic species of Gram-negative coccobacillus, an aerobic bacterium. [1] It is nonspore-forming, nonmotile, [2] and the causative agent of tularemia, the pneumonic form of which is often lethal without treatment. It is a fastidious, facultative intracellular bacterium, which requires cysteine for growth. [3]
Tularemia, also known as rabbit fever, is an infectious disease caused by the bacterium Francisella tularensis. [4] Symptoms may include fever , skin ulcers , and enlarged lymph nodes . [ 3 ] Occasionally, a form that results in pneumonia or a throat infection may occur.
Tularemia, a disease caused by the bacterium Francisella tularensis and commonly transmitted by a tick, deerfly and/or handling the body of a sick or dead infected animal. It may also be ...
Francisella endosymbionts are often misidentified as Francisella tularensis; however, Francisella endosymbionts lack virulence genes and cannot infect humans. [5] The genus was named in honor of American bacteriologist Edward Francis, who, in 1922, first recognized F. tularensis (then named Bacterium tularensis) as the causative agent of ...
Cases of tularemia — a rare and sometimes fatal infectious disease that is also known commonly as “rabbit fever” — have risen in the US in recent years. Between 2011 and 2022, there’s ...
An increase in tularemia infections in Minnesota animals prompted a warning from state health officials, particularly to cat owners, who could get sick if their pets get infected and scratch or ...
Dermacentor variabilis, also known as the American dog tick or wood tick, is a species of tick that is known to carry bacteria responsible for several diseases in humans, including Rocky Mountain spotted fever and tularemia (Francisella tularensis). It is one of the best-known hard ticks. Diseases are spread when it sucks blood from the host.
FtrC (Francisella tularensis sRNA C) is the first sRNA shown to modulate the virulence capacity of F. tularensis. High expression of FtrC reduces intracellular multiplication of the bacteria in macrophages and in organs of infected mice. FtrC mRNA target gene was also identified, but it is not involved in Francisella multiplication. [3]