Search results
Results from the WOW.Com Content Network
The Golgi apparatus (/ ˈ ɡ ɒ l dʒ i /), also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells. [1] Part of the endomembrane system in the cytoplasm , it packages proteins into membrane-bound vesicles inside the cell before the vesicles are sent to their destination.
The cell bodies of Golgi type I neurons are medium-to-large. [24] A Golgi type I neuron has a long axon that begins in the grey matter of the central nervous system and may extend from there. Their cell bodies were mostly multipolar, yet occasionally they might have been triangular in shape and lacking any appendages or spines.
Since the ER is the site of protein synthesis, it would serve as the parent organelle, and the cis face of the golgi, where proteins and signals are received, would be the acceptor. In order for the transport vesicle to accurately undergo a fusion event, it must first recognize the correct target membrane then fuse with that membrane.
The Golgi apparatus consists of multiple membranous sacs, responsible for manufacturing and shipping out materials such as proteins. Lysosomes are structures that use enzymes to break down substances through phagocytosis , a process that comprises endocytosis and exocytosis .
Molecules are also transported to endosomes from the trans Golgi network and either continue to lysosomes or recycle back to the Golgi apparatus. Endosomes can be classified as early, sorting, or late depending on their stage post internalization. [1] Endosomes represent a major sorting compartment of the endomembrane system in cells. [2]
The signal peptide sequence is removed in the endoplasmic reticulum, yielding a propeptide. The propeptide travels to the Golgi apparatus where it is proteolytically cleaved and processed into multiple peptides. Peptides are packaged into dense core vesicles, where further cleaving and processing, such as C-terminal amidation, can occur.
Then the protein passes through the golgi apparatus, where it is packaged into a vesicle. In the vesicle, more parts are cut off, and it turns into mature insulin. In molecular biology, post-translational modification (PTM) is the covalent process of changing proteins following protein biosynthesis.
The polarity of the microtubules is important for cellular transport, as the motor proteins kinesin and dynein typically move preferentially in the "plus" and "minus" directions respectively, along a microtubule, allowing vesicles to be directed to or from the endoplasmic reticulum and Golgi apparatus. Particularly for the Golgi apparatus ...