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The optic nerve can be at very high risk for damage from insufficient blood supply due to swelling (from lack of oxygen) in a confined bony space resulting in a compartment syndrome. Restricted blood flow can lead to permanent damage to the optic nerve and result in blindness (often in both eyes).
Temporary vasospasm leading to decreased blood flow can be a cause of amaurosis fugax. [14] [15] Generally, these episodes are brief, lasting no longer than five minutes, [16] and have been associated with exercise. [10] [17] These vasospastic episodes are not restricted to young and healthy individuals. "Observations suggest that a systemic ...
Ischemia or ischaemia is a restriction in blood supply to any tissue, muscle group, or organ of the body, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive). [ 3 ] [ 4 ] Ischemia is generally caused by problems with blood vessels , with resultant damage to or dysfunction of tissue i.e. hypoxia and ...
NAION is a rare condition that causes a lack of blood flow to part of the optic nerve, which connects the eye to the brain. Without blood flow, the affected areas swell up, stop working correctly ...
Ischemia, meaning insufficient blood flow to a tissue, can also result in hypoxia in the affected tissues. This is called 'ischemic hypoxia'. Ischemia can be caused by an embolism, a heart attack that decreases overall blood flow, trauma to a tissue that results in damage reducing perfusion, and a variety of other causes.
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.
The central retinal artery supplies blood to all the nerve fibers that form the optic nerve, which carries the visual information to the lateral geniculate nucleus of the thalamus, including those that reach over the fovea. Its blood flow can be revealed by fluorescein angiography or laser Doppler imaging. [4]
The blood–ocular barrier is a barrier created by endothelium of capillaries of the retina and iris, ciliary epithelium and retinal pigment epithelium. [1] It is a physical barrier between the local blood vessels and most parts of the eye itself, and stops many substances including drugs from traveling across it. [2]