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Tetracycline (this antibiotic loses its effectiveness after expiration, though scientists are still researching this) Nitroglycerin (taken as heart medication) Insulin
Minocycline, like most tetracyclines, becomes dangerous past its expiration date. [54] While most prescription drugs lose potency after their expiration dates, tetracyclines are known to become toxic over time. Expired tetracyclines can cause serious damage to the kidney due to the formation of a degradation product, anhydro-4-epitetracycline. [54]
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
The labeled expiration date is a manufacturer's promise for a time until which the drug will have full efficacy and be safe as manufactured. [4] The labeled expiration date is not an indication of when a drug has become ineffective or unsafe to use. [4] Many drugs are effective for years after their expiration dates. [4]
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The expiration date of pharmaceuticals specifies the date the manufacturer guarantees the full potency and safety of a drug. Most medications continue to be effective and safe for a time after the expiration date. A rare exception is a case of renal tubular acidosis purportedly caused by expired tetracycline. [9]
We waste a lot of food out of fear: experts estimate that $165 billion worth gets tossed each year. But most expiration dates are largely made-up. According to The National Resource Defense ...
In "double tetracycline labeling", a second dose is given 11–14 days after the first dose, and the amount of bone formed during that interval can be calculated by measuring the distance between the two fluorescent labels. [15] Tetracycline is also used as a biomarker in wildlife to detect consumption of medicine- or vaccine-containing baits. [16]